I 1200
4′-O-methyl-8-γ,γ-dimethylallylkaempferol-3-rhamnoside-7-glucoside
489-32-7
puriss
C33H40O15
94%
676.66
Bottle / Drum
18%
Icariin is a chemical compound classified as a flavonol glycoside, a type of flavonoid. It is the 8-prenyl derivative of kaempferol 3,7-O-diglucoside.
Icariin is an inhibitor of human recombinant PDE5 with an IC50 value of 5.9 μM. It is a prenylated flavonol that has been shown to have anti-cancer and antioxidant activity. At a concentration of 1 x 107 mol/L, Icariin induces differentiation of cardiomyocytes and upregulates the expression of cardiac genes. At 20 μg/ml, Icariin increases the proliferation and differentiation of cultured human osteoblasts, which appears to be mediated in part by upregulating bone morphogenetic protein 2 mRNA.
Biochemicals Found in Plants
≥94% (HPLC)
Light yellow to yellow
Powder
223-225 °C (Predicted)
1.56 g/cm3 (Predicted)
Safety Information for this product is unavailable at this time.
484-12-8
60-27-5
520-36-5