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Synonyms: Propanephosphonic anhydride solution, 2,4,6-Tripropyl-1,3,5,2,4,6-trioxatriphosphorinane-2,4,6-trioxide solution, PPACA, T3P®
Propylphosphonic anhydride (T3P) is a reactive n-propyl phosphonic acid cyclic anhydride. It is a mild and low toxic coupling agent used in peptide synthesis.T3P also acts as a promoter and water scavenger in the Friedländer annulation reaction.
P 3035 (OTTO) 1-Propanephosphonic anhydride, 50 wt.% solution in Acetonitrile Cas 68957-94 - used as an acid-amine coupling reagent for the synthesis of 3-(trifluoromethyl)-1H-pyrazole-5-carboxamides which are potent activators of pyruvate kinase M2 (PKM2).
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