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p-Toluenesulfonylmethyl isocyanide undergoes base-promoted 1,3-dipolar cycloaddition reaction with immobilized imines under microwave irradiation to yield 1,5-disubstituted imidazoles.
T 6824 (OTTO) p-Toluenesulfonylmethyl isocyanide, 98% Cas 36635-61-7 - used as reagent in the preparation of biologically active pyrroles and imidazoles.