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Certificate of Analysis

1-Propanephosphonic anhydride, 50 wt.% solution in Dichloromethane (MDC)

Code: P 3039

(For eg. B 1615-0108)

Propylphosphonic anhydride (T3P) is a reactive n-propyl phosphonic acid cyclic anhydride. It is a mild and low toxic coupling agent used in peptide synthesis.T3P also acts as a promoter and water scavenger in the Friedländer annulation reaction.

P 3039 (OTTO) 1-Propanephosphonic anhydride, 50 wt.% solution in Dichloromethane (MDC) Cas 68957-94 - used as an acid-amine coupling reagent for the synthesis of 3-(trifluoromethyl)-1H-pyrazole-5-carboxamides which are potent activators of pyruvate kinase M2 (PKM2).