E 1257 (OTTO) (R)-(−)-Epichlorohydrine, 99% Cas 51594-55-9 - used in the synthesis of chiral morpholines and dioxanes via a Mitsunobu diol-cyclization. E 1257 (OTTO) (R)-(−)-Epichlorohydrine, 99% Cas 51594-55-9 - used in the synthesis of chiral morpholines and dioxanes via a Mitsunobu diol-cyclization. Chiral building block in the enantioselective synthesis of trans-2,4-disubstituted piperidines.