Bis(trimethylsilyl)acetylene (BTMSA) participates as nucleophile in Friedel-Crafts type acylations and alkylations. BTMSA undergoes rhodium catalyzed addition reaction with diarylacetylenes. It undergoes cycloaddition with 1,5-hexadiynes in the presence of CpCo(CO)2 (Cp=cyclopentadienyl) to form benzocyclobutenes.
B 2348 (OTTO) Bis(trimethylsilyl)acetylene, 99% Cas 14630-40-1 - used as starting reagent in the synthesis of functionalized 4-R-1,2-bis(trimethylsilyl)benzenes. B 2348 (OTTO) Bis(trimethylsilyl)acetylene, 99% Cas 14630-40-1 - used in the synthesis of (+)-brasilenyne and (β-diketanato)Ag(BTMSA).