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Synonyms: 1-(m-Chlorophenyl)piperazine, 4-(3-Chlorophenyl)piperazine, N-(3-Chlorophenyl)piperazine
1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans. It is common to several antidepressants including Trazodone, Nefazodone, and Etoperidone. 1-(3-Chlorophenyl)piperazine is a SR-2C (5-HT2C)/SR-2B (5-HT2C) agonist/partial agonist and SR-2A (5-HT2A) antagonist.
A major circulating metabolite in humans.
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