C 0778
Camptothecin
7689-03-4
puriss
C20H16N2O4
2942
90%
348.35
Bottle / Drum
18%
Camptothecin was originally isolated from the stem wood of the Camptotheca acuminata tree and was shown to exhibit antileukemic/antitumor activity, and reversibly inhibit Mitochondrial Topo I (nuclear Topo I (topoisomerase I)) by binding to and stabilizing the topoisomerase-DNA covalent complex.
Camptothecin is a reversible Mitochondrial Topo I inhibitor shown to exhibit antitumor activity
Antibiotics
Solid
260 °C (dec.)(lit.)
2-8°C
RIDADR UN 1544PSN1 6.1 / PGIIIWGK Germany 3
300-08-3
1405-10-3
1405-20-5
22252-43-3