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Custom Peptide Synthesis

Custom peptide synthesis is the commercial production of peptides for use in biochemistry, biology, biotechnology, pharmacology and molecular medicine. Custom peptide synthesis provides synthetic peptides as valuable tools to biomedical laboratories. Synthetic oligopeptides are used extensively in research for structure-function analysis (for example to study protein-protein interfaces), for the development of binding assays, the study of receptor agonist/antagonists or as immunogens for the production of specific antibodies. Generally, peptides are synthesized by coupling the carboxyl group or C-terminus of one amino acid to the amino group or N-terminus of another using automated solid phase peptide synthesis chemistries. However, liquid phase synthesis may also be used for specific needs.

Synthesis

Otto Chemie Pvt Ltd highly experienced team of scientists have synthesized oligomers ranging from µg up to multigram quantities. Since our establishment, we have synthesized more than 1,500 different kinds of peptides. The peptides range from di-peptides to peptides having more than 60 Amino Acid residues.

We provide custom peptides synthesis to customers from the biomedical research community, biotechnology and pharmaceutical industry. We have consistently maintained the highest standards of quality, service and technical expertise.

Methodology

  • Solid phase using Fmoc and t-Boc methodologies.
  • Solution phase chemistry.

Modifications

  • N-terminal acetylation/deamidation
  • C-terminal amidation
  • Site specific peptide modifications
  • Biotinylated peptides
  • Conjugation to KLH, BSA etc
  • Fluorescent tagged peptides
  • Incorporation of unusual amino acids
  • Cyclic and phosphorylated peptides
  • Peptide libraries
  • Chloromethyl Ketone peptides
  • Phosphopeptides

Equipments for Synthesis and Analysis

  • Analytical, Preparative and Semi preparative HPLC
  • Low pressure, Medium pressure and Ion chromatography systems
  • Amino acid analyzers
  • MS
  • LCMS
  • NMR
  • CD
  • GC
  • FTIR
  • Lab scale, Multiple and Large scale peptide synthesizers
  • Lyophilizers
  • Centri Evaporators
Reliability

Reliability

With this facility and our highly experienced team of scientists, the quality of each peptide is individually guaranteed and verified.

Delivery

Delivery

The facility and in-house testing makes it feasible for us to supply the peptides within the shortest possible time.

For more information please contact uspeptide@ottokemi.com