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4-phenylbutanoic acid, 4-Phenylbutyric acid
P 1642
for synthesis
C6H5(CH2)3COOH
291560.20
18%
1821-12-1
98%
164.20
Bottle / Drum
P 1642 (OTTO) 4-Phenylbutyric acid, 98% Cas 1821-12-1 - used as a chemical chaperone involved in protein-folding disorders. It is involved in the synthesis of dyes and an active pharmaceutical ingredient intermediate.
4-Phenylbutyric acid is a chemical chaperone, which suppresses oxidative stress by attenuating endoplasmic reticulum stress. 4-Phenylbutyric acid increases the expression of type 2 deiodinase (D2), via the accumulation of Dio2 mRNA. Studies indicate that 4-Phenylbutyric acid affects genes such as Ucp-1, Ucp-3 and Pgc-1α in a D2-dependent manner. The activation of these genes is thought to increase T3 production. Diabetic studies conducted on mice suggest that 4-Phenylbutyric acid normalizes serum glucose levels.
Carbonyl compounds, Carboxylic acids
98%+
Powder or crystals
White to off-white
49-53 °C
Safety Statements 22-24/25WGK Germany 3
DisclaimerThe above particulars do not release the customer from the obligation to carry out an inspection of goods received. For laboratory use only. Not for drug, medical, household, or any other unauthorized application. We assume no liability for misuse or unauthorized application of the product. Please test before use.